Sildenafil Protocol

Physician Services›Sexual Health›Sildenafil Compounded
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PDE5 Inhibitor · Physician Services

Sildenafil Compounded

Compounded Tablet/ODT · Oral · Physician Supervised
How this works: Clicking any option below takes you to the TeleWellnessMD® platform where a licensed medical provider reviews your information. An initial consultation is required. Compounded medications are not FDA-approved as safe and effective for the treatment of any disease or condition.
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About This Protocol

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor that works by blocking the enzyme that breaks down cyclic GMP in smooth muscle tissue. Elevated cGMP levels cause smooth muscle relaxation and vasodilation, supporting vascular function. This is a compounded formulation.

Available through licensed TeleWellnessMD® providers in select states. Multiple dose forms and strengths available. Physician evaluation required.

PDE5 Inhibition Mechanism
PDE5 is expressed primarily in the smooth muscle of blood vessels and the corpus cavernosum. By inhibiting PDE5, sildenafil prevents the breakdown of cGMP — the second messenger that causes smooth muscle relaxation and vasodilation in response to nitric oxide signaling.
Onset and Duration
Standard sildenafil has an onset of approximately 30-60 minutes and duration of 4-6 hours. The ODT form may have faster onset due to sublingual absorption. Patients taking nitrates cannot use PDE5 inhibitors due to risk of severe hypotension.
Compounded vs. FDA Approved
Compounded sildenafil is not FDA-approved as safe and effective. FDA-approved versions of sildenafil exist as brand-name products. Compounded versions are prepared by licensed pharmacies for patients with specific needs.
Contraindications
PDE5 inhibitors are contraindicated with nitrate medications, certain alpha-blockers, and in patients with specific cardiovascular conditions. Physician evaluation is essential to identify contraindications before prescribing.

Available Options

Select the option appropriate for your current protocol stage. If you are new, begin with the starting dose. Your physician will guide progression based on your individual response and medical evaluation.


Standard Tablet 100mg
Sildenafil
100mg Tablet · 30 Count
$109.95
No supplies needed
Begin Evaluation
Physician approval required

Low Dose Tablet 20mg
Sildenafil
20mg Tablet · 30 Count
$109.95
No supplies needed
Begin Evaluation
Physician approval required

ODT 115mg
Sildenafil
115mg ODT · 10 Count
$149.95
No supplies needed
Begin Evaluation
Physician approval required

What to Expect

After selecting an option above you will be directed to the TeleWellnessMD® platform. A licensed medical provider will review your health information and determine whether this protocol is appropriate for you. An initial consultation is required before any prescription can be issued. Prescription availability varies by state.

Results and side effects vary from patient to patient. These reports do not constitute medical claims.

Not Sure Where to Start?

Speak with a Licensed Provider

Start with a free physician assessment. A TeleWellnessMD® provider will evaluate your situation and recommend the appropriate protocol.

Start Free Assessment →
25% off your first order · Automatically applied · TeleWellnessMD® · Physician determines medical necessity

Compounded medications are not FDA-approved as safe and effective for the treatment of any disease or condition. The FDA does not review compounded formulations for safety, effectiveness, or quality. Compounded medications are prepared by a state-regulated licensed pharmacy in accordance with a prescriber's order. Results and side effects may vary from patient to patient. The Vitality Stack is an advertising affiliate of TeleWellnessMD® and may earn a commission if you complete a purchase. This content is for educational and advertising purposes only and does not constitute medical advice. Consult a licensed physician before starting any medication protocol. TeleWellnessMD® physicians exercise independent professional medical judgment in all prescribing decisions.