IGF1 Protocol

Physician Services›Athletic Performance›IGF-1 LR3 Protocol
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Peptide Therapy · Physician Services

IGF-1 LR3 Protocol

Compounded Injectable Peptide · Long R3 Analog · Physician Supervised
How this works: Clicking any option below takes you to the TeleWellnessMD® platform where a licensed medical provider reviews your information. An initial consultation is required. Compounded medications are not FDA-approved as safe and effective for the treatment of any disease or condition.
25%
First Order Discount
Save 25% on your first order — automatically applied
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About This Protocol

IGF-1 LR3 is a synthetic analog of Insulin-like Growth Factor 1 with an arginine substitution at position 3 and an additional 13-amino acid extension at the N-terminus. These modifications reduce binding to IGF-1 binding proteins, extending its active half-life from minutes to hours compared to native IGF-1.

Available through licensed TeleWellnessMD® providers in select states. Physician determines protocol, dosing schedule, and monitoring requirements.

Extended Half-Life
Native IGF-1 has a half-life of minutes due to rapid binding by circulating IGF-1 binding proteins (IGFBPs). The Long R3 modification reduces IGFBP binding affinity by approximately 1000-fold, extending the half-life to 20-30 hours and significantly increasing free peptide availability.
Downstream of Growth Hormone
IGF-1 is the primary mediator of growth hormone's anabolic effects. GH stimulates hepatic IGF-1 production, which then acts on muscle, bone, and connective tissue to stimulate protein synthesis and cellular proliferation through the IGF-1R receptor.
Research Context
IGF-1 research has examined its roles in muscle protein synthesis, satellite cell activation, and tissue repair. Studies in aging populations have examined IGF-1's relationship with muscle mass maintenance and physical function.
Monitoring Requirements
IGF-1 protocols require physician monitoring of IGF-1 blood levels, glucose response, and other markers. The physician determines appropriate dosing, frequency, and monitoring schedule based on individual patient assessment.

Available Options

Select the option appropriate for your current protocol stage. If you are new, begin with the starting dose. Your physician will guide progression based on your individual response and medical evaluation.


2-Vial Kit
IGF-1 LR3
600mcg Lyophilized · ×2 Vials
$449.95
Vials ×2 · 31g syringes ×24 · Alcohol wipes ×24
Begin Evaluation
Physician approval required

4-Vial Kit
IGF-1 LR3
600mcg Lyophilized · ×4 Vials
$759.95
Vials ×4 · 31g syringes ×24 · Alcohol wipes ×24
Begin Evaluation
Physician approval required

What to Expect

After selecting an option above you will be directed to the TeleWellnessMD® platform. A licensed medical provider will review your health information and determine whether this protocol is appropriate for you. An initial consultation is required before any prescription can be issued. Prescription availability varies by state.

Results and side effects vary from patient to patient. These reports do not constitute medical claims.

Not Sure Where to Start?

Speak with a Licensed Provider

Start with a free physician assessment. A TeleWellnessMD® provider will evaluate your situation and recommend the appropriate protocol.

Start Free Assessment →
25% off your first order · Automatically applied · TeleWellnessMD® · Physician determines medical necessity

Compounded medications are not FDA-approved as safe and effective for the treatment of any disease or condition. The FDA does not review compounded formulations for safety, effectiveness, or quality. Compounded medications are prepared by a state-regulated licensed pharmacy in accordance with a prescriber's order. Results and side effects may vary from patient to patient. The Vitality Stack is an advertising affiliate of TeleWellnessMD® and may earn a commission if you complete a purchase. This content is for educational and advertising purposes only and does not constitute medical advice. Consult a licensed physician before starting any medication protocol. TeleWellnessMD® physicians exercise independent professional medical judgment in all prescribing decisions.